Published On: Tue, Jul 14th, 2015

New gene therapy process provides specific, protected control of healing transgenes

Korean researchers have described a novel control complement to umpire a countenance of a healing transgene by targeting a newcomer strand of a microRNA (miR-122) related to a transgene. The researchers news that a control complement formed on targeting a newcomer strand of miR-122 rather than a beam strand can umpire countenance of an exogenous, healing gene, while not inspiring a countenance of endogenous genes, in an essay in Nucleic Acid Therapeutics. The essay is accessible giveaway on a Nucleic Acid Therapeutics website until Aug 13, 2015.

Sung Jin Kim, Chang Ho Lee, and Seong-Wook Lee, Dankook University, Yongin, Republic of Korea, report a novel gene therapy control complement they grown in a essay “Targeting a MicroRNA Passenger Strand for Regulating Therapeutic Transgenes”. They review a formula of studies to umpire a countenance of a transgene by targeting possibly a beam or newcomer strand of miR-122, and plead a underlying mechanisms to explain a celebrated miRNA activity and up- and down-regulation of gene expression.

“This transparent and convincing paper proposes a new, safe, and effective proceed to umpire healing transgenes,” says Executive Editor Graham C. Parker, PhD, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Children’s Hospital of Michigan, Detroit, MI.

Source: Mary Ann Liebert, Inc./Genetic Engineering News

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