First person

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Judith S. Cruz Ortega is first author on ‘Actin cytoskeleton remodeling defines a distinct cellular function for adhesion G protein-coupled receptors More...

by Kalen Beh | Published 2 years ago
By Kalen Beh On Tuesday, April 23rd, 2019
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penner/lgl2 is required for the integrity of the photoreceptor layer in the zebrafish retina [RESEARCH ARTICLE]

DISCUSSION In vertebrates, proper vision depends on the correct specification and differentiation of several neuronal cell types, the formation of synaptic contacts between them and their organization into a highly More...

By Kalen Beh On Tuesday, April 23rd, 2019
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Characterization and comparative analyses of transcriptomes of cloned and in vivo fertilized porcine pre-implantation embryos [RESEARCH ARTICLE]

DISCUSSION Multi-omics sequencing of various species has developed rapidly, and several recent studies have reported the gene expression dynamics of human and mouse pre-implantation embryos by RNA-Seq, which has More...

By Kalen Beh On Tuesday, April 23rd, 2019
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Actin cytoskeleton remodeling defines a distinct cellular function for adhesion G protein-coupled receptors ADGRL/latrophilins 1, 2 and 3 [RESEARCH ARTICLE]

Cover article – Serum-based inhibition of pitviper venom by eastern indigo snakes (Drymarchon couperi) Image credit Scott Goetz: an eastern indigo snake (Drymarchon couperi). Scott Goetz and colleagues confirm More...

By Kalen Beh On Thursday, April 18th, 2019
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First person

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Kingsley Ugwuagbo More...

By Kalen Beh On Thursday, April 18th, 2019
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Higher incubation temperatures produce long-lasting upward shifts in cold tolerance, but not heat tolerance, of hatchling geckos [RESEARCH ARTICLE]

DISCUSSION Developmental plasticity coupled with short-term heat hardening could potentially buffer lizards from the effects of summer heatwaves. In this study, we subjected developing embryos of the velvet gecko More...

By Kalen Beh On Thursday, April 18th, 2019
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Prostaglandin E2 promotes embryonic vascular development and maturation in zebrafish [RESEARCH ARTICLE]

INTRODUCTION Prostaglandin (PG) E-2 is a prostanoid, which is endogenously synthesized from the arachidonic acid of vertebrate cell membranes by an enzyme, cyclooxygenase (COX)-2. PGE2 binds to four different G-coupled More...

By Kalen Beh On Thursday, April 18th, 2019
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The chromodomain helicase CHD4 regulates ERBB2 signaling pathway and autophagy in ERBB2+ breast cancer cells [RESEARCH ARTICLE]

INTRODUCTION Breast cancer (BC) is considered a collection of diseases showing heterogeneity at molecular, histopathological and clinical level, which generates variable clinical courses and responses to treatments More...

By Kalen Beh On Thursday, April 18th, 2019
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Transcriptomic analysis of Spodoptera frugiperda Sf9 cells resistant to Bacillus thuringiensis Cry1Ca toxin reveals that extracellular Ca2+, Mg2+ and production of cAMP are involved in toxicity [RESEARCH ARTICLE]

DISCUSSION In this report, we describe Sf9 cells resistant to the Cry1Ca toxin obtained after a selection program. We tested Sf9wt cells for their sensitivity to another Cry toxin (Cry1Ab) at toxin concentrations More...

By Kalen Beh On Tuesday, April 16th, 2019
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Nematicidal actions of the marigold exudate {alpha}-terthienyl: oxidative stress-inducing compound penetrates nematode hypodermis [RESEARCH ARTICLE]

DISCUSSION α-terthienyl is photoactivated generator of singlet oxygen and superoxide anion radicals (Huang et al., 2017; Nivsarkar et al., 2001). Mosquito larval mortality was 100% after treatment with naturally More...