Infective larvae of Anisakis simplex (Nematoda) accumulate trehalose and glycogen in response to starvation and temperature stress [RESEARCH ARTICLE]

DISCUSSION Parasitic nematodes have developed numerous physiological and biochemical adaptive mechanisms supporting survival under adverse environmental conditions, such as thermal and osmotic shock, starvation and unfavorable pH (Wharton et al., 2000; Erkut et al., 2013). The molecular and biochemical bases of these adaptive traits have to be identified More...

by Kalen Beh | Published 2 days ago
By Kalen Beh On Monday, March 18th, 2019
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First person

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Maika S. Deffieu More...

By Kalen Beh On Monday, March 18th, 2019
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First person

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Kyle Wegner More...

By Kalen Beh On Monday, March 18th, 2019
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The Toxoplasma gondii dense granule protein TgGRA3 interacts with host Golgi and dysregulates anterograde transport [RESEARCH ARTICLE]

DISCUSSION In this study, we revealed one of the molecular mechanisms of host organelle recruitment by the parasite T. gondii. Combining biochemical approaches and mass spectrometry, we showed that TgGRA3 interacts More...

By Kalen Beh On Monday, March 18th, 2019
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Odd-skipped and Stripe act downstream of Notch to promote the morphogenesis of long appendicular tendons in Drosophila [RESEARCH ARTICLE]

Both Odd-family and Stripe are required for tube-like tendon formation As odd genes are targets of Notch signaling, and leg disc epithelium folding has already been described upon ectopic expressions of odd genes More...

By Kalen Beh On Monday, March 18th, 2019
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Mbt/PAK4 together with SRC modulates N-Cadherin adherens junctions in the developing Drosophila eye [RESEARCH ARTICLE]

INTRODUCTION Tissue morphogenesis in animals is accompanied by changes in composition of the zonula adherens (ZA) allowing dynamic intercellular interactions. In developmental processes, ZA becomes manifold reorganized More...

By Kalen Beh On Monday, March 18th, 2019
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Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate [RESEARCH ARTICLE]

Author contributions Conceptualization: K.A.W., V.M., J.A.J., K.P.K., L.L.A., D.J.H., C.M.V.; Methodology: K.A.W., V.M., J.A.J., B.R.M., K.P.K., L.L.A., M.M.T., C.M.V.; Software: C.M.V.; Validation: K.A.W., V.M., More...

By Kalen Beh On Thursday, March 14th, 2019
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Identification of possible hypoxia sensor for behavioral responses in a marine annelid, Capitella teleta [RESEARCH ARTICLE]

DISCUSSION Hypoxia treatment induced escape behavior of C. teleta, and this behavior was suppressed by the administration of A-967079 (Fig. 1), while the locomotor activity was not suppressed by A-967079 (Fig. S1). More...

By Kalen Beh On Wednesday, March 13th, 2019
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First person

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Ana Cecilia More...

By Kalen Beh On Tuesday, March 12th, 2019
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Reprogramming of the cambium regulators during adventitious root development upon wounding of storage tap roots in radish (Raphanus sativus L.) [RESEARCH ARTICLE]

PXY-WOX4 may be reprogramed to aid the adventitious root formation Founder cells of ARs seemed to be derived from the cambium. During this reprogramming the cut radish taproots no longer grew in the radial direction More...